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Neonatal Group B Streptococcal Disease

  • Robert S. Howe
  • , Tomasz H. Voychehovski
  • , Faheem Uraizee
  • , Christopher Bentsen
  • , Michael L. Spear
  • , Howard Minkoff
  • , Philip Mead
  • , Kenneth M. Boyer
  • , Samuel P. Gotoff
  • University of Pennsylvania
  • Cincinnati Children's Hospital Medical Center
  • SUNY Upstate Medical University
  • DuPont
  • Medical Center of Delaware
  • University of Vermont
  • Rush University Medical Center

Research output: Contribution to journalLetterpeer-review

7 Scopus citations

Abstract

To the Editor: Boyer and Gotoff (June 26 issue)1 have shown the value of prophylactic ampicillin to prevent early-onset neonatal group B streptococcal sepsis. They suggest latex-agglutination assays as a way to identify fetuses at risk.2 3 4 5 In a prospective study of 162 infants born alive and their mothers, we examined the ability of six laboratory tests to predict the onset of group B streptococcal sepsis. All infants weighed more than 500 g and were at high risk for streptococcal sepsis as a result of prolonged membrane rupture, prematurity, a positive maternal cervical culture, intrapartum fever, a five-minute Apgar score below…

Original languageEnglish
Pages (from-to)1163-1164
Number of pages2
JournalNew England Journal of Medicine
Volume316
Issue number18
DOIs
StatePublished - Apr 30 1987

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