Abstract
Electrical stimulation of the medial prefrontal cortex (MFC) induced a moderate behavioral suppression in a series of neurological tests that included measures of (1) open field activity (2) righting and climbing reflexes (3) somatosensory reactivity and (4) approach-withdrawal responsivity to positive and negative stimuli. The same animals were trained to lever press for medial prefrontal cortex stimulation and after several days of self-stimulation were again tested for neurological reactivity during MFC stimulation. No habituation or lessening of behavioral suppression was evident as a result of self-stimulation experience. Therefore behavioral suppression, by itself, cannot account for the slow acquisition of MFC self-stimulation. Other data suggest that the stimulation interferes with the learning of complex operant responses and/or that the reward value of the stimulation is increased as a result of repetition.
| Original language | English |
|---|---|
| Pages (from-to) | 771-776 |
| Number of pages | 6 |
| Journal | Physiology and Behavior |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1983 |
Keywords
- Neurological testing
- Prefrontal cortex
- Self-stimulation
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