Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification

Patricia M. Kane

doi:10.1083/jcb.202412054

Newborn daughters get a fresh start through PI(3,5)P₂-mediated vacuolar acidification

Patricia M. Kane

Biochemistry & Molecular Biology

Upstate Medical University

Research output: Contribution to journal › Comment/debate

Abstract

Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle–dependent increase in PI(3,5)P₂ levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.

Original language	English
Article number	e202412054
Journal	Journal of Cell Biology
Volume	224
Issue number	1
DOIs	https://doi.org/10.1083/jcb.202412054
State	Published - Jan 6 2025

Access to Document

10.1083/jcb.202412054

Cite this

@article{42959f91739345d096158b0eab1d9b94,

title = "Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification",

abstract = "Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle–dependent increase in PI(3,5)P2 levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.",

author = "Kane, \{Patricia M.\}",

note = "Publisher Copyright: {\textcopyright} 2024 Kane.",

year = "2025",

month = jan,

day = "6",

doi = "10.1083/jcb.202412054",

language = "English",

volume = "224",

journal = "Journal of Cell Biology",

issn = "0021-9525",

number = "1",

}

TY - JOUR

T1 - Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification

AU - Kane, Patricia M.

PY - 2025/1/6

Y1 - 2025/1/6

N2 - Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle–dependent increase in PI(3,5)P2 levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.

AB - Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle–dependent increase in PI(3,5)P2 levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.

UR - https://www.scopus.com/pages/publications/85213528415

U2 - 10.1083/jcb.202412054

DO - 10.1083/jcb.202412054

M3 - Comment/debate

C2 - 39705073

SN - 0021-9525

VL - 224

JO - Journal of Cell Biology

JF - Journal of Cell Biology

IS - 1

M1 - e202412054

ER -

Newborn daughters get a fresh start through PI(3,5)P₂-mediated vacuolar acidification

Abstract

Access to Document

Other files and links

Fingerprint

Cite this