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Noninvasive high-resolution detection of the arterial and venous input function through a PET Wrist Scanner

  • A. Kriplani
  • , S. P. Stoll
  • , S. Southekal
  • , D. J. Schlyer
  • , S. J. Park
  • , A. Villanueva
  • , J. F. Pratte
  • , S. Junnarkar
  • , P. Vaska
  • , C. L. Woody
  • Stony Brook University
  • Brookhaven National Laboratory

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Scopus citations

Abstract

In order to assess the kinetics of radiotracer accumulation in tissue, the amount of radioactivity in the blood must be quantitatively measured as an input function to the kinetic model. Due to safety and comfort issues with invasive determination of the input function, a non-invasive method for arterial measurement of blood radioactivity is investigated using a wrist scanner. A prototype consisting of two detector pairs of LSO and APD detector arrays is used to obtain planar images of an anatomically correct wrist phantom. The spatial resolution and sensitivity of the prototype is determined. The results showed the detector was able to discriminate the arterial and venous flows from each other when using planar coincidence images.

Original languageEnglish
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Pages2240-2244
Number of pages5
DOIs
StatePublished - 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume4

Conference

ConferenceNuclear Science Symposium Conference Record, 2005 IEEE
Country/TerritoryPuerto Rico
Period10/23/0510/29/05

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