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Optree: A learning-based adaptive watershed algorithm for neuron segmentation

  • Mustafa Gökhan Uzunbaş
  • , Chao Chen
  • , Dimitris Metaxsas
  • Rutgers - The State University of New Jersey, New Brunswick

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

22 Scopus citations

Abstract

We present a new algorithm for automatic and interactive segmentation of neuron structures from electron microscopy (EM) images. Our method selects a collection of nodes from the watershed merging tree as the proposed segmentation. This is achieved by building a conditional random field (CRF) whose underlying graph is the merging tree. The maximum a posteriori (MAP) prediction of the CRF is the output segmentation. Our algorithm outperforms state-of-the-art methods. Both the inference and the training are very efficient as the graph is tree-structured. Furthermore, we develop an interactive segmentation framework which selects uncertain regions for a user to proofread. The uncertainty is measured by the marginals of the graphical model. Based on user corrections, our framework modifies the merging tree and thus improves the segmentation globally.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI 2014 - 17th International Conference, Proceedings
PublisherSpringer Verlag
Pages97-105
Number of pages9
EditionPART 1
ISBN (Print)9783319104034
DOIs
StatePublished - 2014
Event17th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014 - Boston, MA, United States
Duration: Sep 14 2014Sep 18 2014

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 1
Volume8673 LNCS

Conference

Conference17th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014
Country/TerritoryUnited States
CityBoston, MA
Period09/14/1409/18/14

Keywords

  • Conditional Random Field
  • EM Segmentation
  • User Interaction
  • Watershed

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