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Pain, Fear, Anxiety, and Stress: Relations to the Endogenous Opioid System

  • West Virginia University
  • Marquette University
  • University of Florida

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Pain, fear, stress, and anxiety are separate yet interrelated phenomena. Each of these concepts has an extensive individual body of research, with some more recent work focusing on points of conceptual overlap. The role of the endogenous opioid system in each of these phenomena is only beginning to be examined and understood. Research examining the ways in which endogenous opioids (e.g., beta-endorphin; βE) may mediate the relations among pain, fear, stress, and anxiety is even more nascent. This chapter explores the extant evidence for endogenous opioid activity as an underpinning mechanism of these related constructs, with an emphasis on research examining βE.

Original languageEnglish
Title of host publicationAdvances in Neurobiology
PublisherSpringer
Pages157-182
Number of pages26
DOIs
StatePublished - 2024

Publication series

NameAdvances in Neurobiology
Volume35

Keywords

  • Anxiety
  • Endogenous opioids
  • Endorphins
  • Pain

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