Abstract
We study a general class of piecewise Cox models. We discuss the computation of the semi-parametric maximum likelihood estimates (SMLE) of the parameters, with right-censored data, and a simplified algorithm for the maximum partial likelihood estimates (MPLE). Our simulation study suggests that the relative efficiency of the PMLE of the parameter to the SMLE ranges from 96% to 99.9%, but the relative efficiency of the existing estimators of the baseline survival function to the SMLE ranges from 3% to 24%. Thus, the SMLE is much better than the existing estimators.
| Original language | English |
|---|---|
| Pages (from-to) | 7894-7908 |
| Number of pages | 15 |
| Journal | Communications in Statistics: Simulation and Computation |
| Volume | 46 |
| Issue number | 10 |
| DOIs | |
| State | Published - Nov 26 2017 |
Keywords
- Cox model
- Semi-parametric MLE
- Time-dependent covariates
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