Postnatal gene therapy improves spatial learning despite the presence of neuronal ectopia in a model of neuronal migration disorder

Keyphrases

• Gene Therapy 100%
• Neuronal Migration Defect 100%
• Ectopia 100%
• Spatial Learning 100%
• Knock-in Mouse Model 66%
• Glycosylation 50%
• Learning Impairment 50%
• Barnes Maze 50%
• Cerebral Cortex 33%
• Protein O-mannosyltransferase 33%
• Specificity Protein 1 16%
• Effective Therapy 16%
• Latency 16%
• Fetal Development 16%
• Performance Improvement 16%
• Type II Lissencephaly 16%
• Cognitive Deficits 16%
• Postnatal Brain 16%
• CA1 Neurons 16%
• Adeno-associated Viral Vector 16%
• Learning Improvement 16%
• Dendritic Spines 16%
• Encoded Protein 16%
• Dendritic Spine Density 16%
• Vector Encoding 16%
• Ectopic Neurons 16%

Neuroscience

• Barnes Maze 100%
• Learning Disability 100%
• Glycosylation 100%
• Neuronal Migration 100%
• Cerebral Cortex 66%
• Dendritic Spine 66%
• Mannosyltransferase 66%
• Cognitive Disorder 33%
• Adeno Associated Virus Vector 33%
• Lissencephaly 33%