Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT

David J. Lubin; Stuart B. Holden; Matthew B. Rettig; Robert E. Reiter; Christopher R. King; Jay M. Lee; Dean W. Wallace; Jeremie Calais

doi:10.1097/RLU.0000000000002499

Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT

David J. Lubin
, Stuart B. Holden
, Matthew B. Rettig
, Robert E. Reiter
, Christopher R. King
, Jay M. Lee
, Dean W. Wallace
, Jeremie Calais

Radiology

Upstate Medical University

Institute of Urologic Oncology
Division of Thoracic Surgery
University of California at Los Angeles

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

68Ga-prostate-specific membrane antigen 11 (PSMA) PET/CT imaging accurately depicts metastatic prostate adenocarcinoma (PCa). Pulmonary metastases of PCa are often overlooked on follow-up imaging in patients after initial treatment and following androgen deprivation therapy. Here we present a rare case of biopsy-proven PCa pulmonary metastasis with a ground-glass appearance. The increased PSMA expression and the evolving CT features of the solid component of the ground-glass nodule detected by PSMA PET/CT imaging led to surgical resection and PET/CT-guided therapy.

Original language	English
Pages (from-to)	E353-E356
Journal	Clinical Nuclear Medicine
Volume	44
Issue number	5
DOIs	https://doi.org/10.1097/RLU.0000000000002499
State	Published - May 1 2019

Keywords

PSMA PET/CT
ground-glass pulmonary nodule
metastasis
prostate cancer

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10.1097/RLU.0000000000002499

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title = "Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT",

abstract = "68Ga-prostate-specific membrane antigen 11 (PSMA) PET/CT imaging accurately depicts metastatic prostate adenocarcinoma (PCa). Pulmonary metastases of PCa are often overlooked on follow-up imaging in patients after initial treatment and following androgen deprivation therapy. Here we present a rare case of biopsy-proven PCa pulmonary metastasis with a ground-glass appearance. The increased PSMA expression and the evolving CT features of the solid component of the ground-glass nodule detected by PSMA PET/CT imaging led to surgical resection and PET/CT-guided therapy.",

keywords = "PSMA PET/CT, ground-glass pulmonary nodule, metastasis, prostate cancer",

author = "Lubin, \{David J.\} and Holden, \{Stuart B.\} and Rettig, \{Matthew B.\} and Reiter, \{Robert E.\} and King, \{Christopher R.\} and Lee, \{Jay M.\} and Wallace, \{Dean W.\} and Jeremie Calais",

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doi = "10.1097/RLU.0000000000002499",

language = "English",

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T1 - Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT

AU - Lubin, David J.

AU - Holden, Stuart B.

AU - Rettig, Matthew B.

AU - Reiter, Robert E.

AU - King, Christopher R.

AU - Lee, Jay M.

AU - Wallace, Dean W.

AU - Calais, Jeremie

PY - 2019/5/1

Y1 - 2019/5/1

N2 - 68Ga-prostate-specific membrane antigen 11 (PSMA) PET/CT imaging accurately depicts metastatic prostate adenocarcinoma (PCa). Pulmonary metastases of PCa are often overlooked on follow-up imaging in patients after initial treatment and following androgen deprivation therapy. Here we present a rare case of biopsy-proven PCa pulmonary metastasis with a ground-glass appearance. The increased PSMA expression and the evolving CT features of the solid component of the ground-glass nodule detected by PSMA PET/CT imaging led to surgical resection and PET/CT-guided therapy.

AB - 68Ga-prostate-specific membrane antigen 11 (PSMA) PET/CT imaging accurately depicts metastatic prostate adenocarcinoma (PCa). Pulmonary metastases of PCa are often overlooked on follow-up imaging in patients after initial treatment and following androgen deprivation therapy. Here we present a rare case of biopsy-proven PCa pulmonary metastasis with a ground-glass appearance. The increased PSMA expression and the evolving CT features of the solid component of the ground-glass nodule detected by PSMA PET/CT imaging led to surgical resection and PET/CT-guided therapy.

KW - PSMA PET/CT

KW - ground-glass pulmonary nodule

KW - metastasis

KW - prostate cancer

UR - https://www.scopus.com/pages/publications/85064239362

U2 - 10.1097/RLU.0000000000002499

DO - 10.1097/RLU.0000000000002499

M3 - Article

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SN - 0363-9762

VL - 44

SP - E353-E356

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

IS - 5

ER -

Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT

Abstract

Keywords

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