Protein Transport to Photoreceptor Outer Segments

Peter D. Calvert

doi:10.1016/B978-0-443-13820-1.00064-5

Protein Transport to Photoreceptor Outer Segments

Peter D. Calvert

Upstate Medical University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The operation of photoreceptors as sensory neurons critically relies on compartmentalization of key functions into three major cellular regions. The ciliary outer segment contains the phototransduction machinery, the inner segment/cell body houses protein expression and processing, and the pre-synapse contains the machinery responsible for relaying photoreceptor electrical activity to downstream neurons. The mechanisms by which proteins that subserve these functions are compartmentalized are the subject of intense study.

Original language	English
Title of host publication	Encyclopedia of the Eye
Publisher	Elsevier
Pages	V3:95-V3:102
ISBN (Electronic)	9780443138201
ISBN (Print)	9780443138393
DOIs	https://doi.org/10.1016/B978-0-443-13820-1.00064-5
State	Published - Jan 1 2025

Keywords

Diffusion
Functional compartments
Intrinsic membrane protein
Membranes
Outer segment
Peripheral membrane protein
Photoreceptors
Protein transport
Secretion
Soluble protein

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10.1016/B978-0-443-13820-1.00064-5

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keywords = "Diffusion, Functional compartments, Intrinsic membrane protein, Membranes, Outer segment, Peripheral membrane protein, Photoreceptors, Protein transport, Secretion, Soluble protein",

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AB - The operation of photoreceptors as sensory neurons critically relies on compartmentalization of key functions into three major cellular regions. The ciliary outer segment contains the phototransduction machinery, the inner segment/cell body houses protein expression and processing, and the pre-synapse contains the machinery responsible for relaying photoreceptor electrical activity to downstream neurons. The mechanisms by which proteins that subserve these functions are compartmentalized are the subject of intense study.

KW - Diffusion

KW - Functional compartments

KW - Intrinsic membrane protein

KW - Membranes

KW - Outer segment

KW - Peripheral membrane protein

KW - Photoreceptors

KW - Protein transport

KW - Secretion

KW - Soluble protein

UR - https://www.scopus.com/pages/publications/105028837576

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DO - 10.1016/B978-0-443-13820-1.00064-5

M3 - Chapter

SN - 9780443138393

SP - V3:95-V3:102

BT - Encyclopedia of the Eye

PB - Elsevier

ER -

Protein Transport to Photoreceptor Outer Segments

Abstract

Keywords

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