Quantification of hypoperfusion in autism spectrum disorder assessed by diffuse correlation spectroscopy

Benjamin Rinehart; Chien Poon; Ulas Sunar

Quantification of hypoperfusion in autism spectrum disorder assessed by diffuse correlation spectroscopy

Benjamin Rinehart
, Chien Poon
, Ulas Sunar

Dept of Biomedical Engineering

Stony Brook University

Wright State University

Research output: Contribution to journal › Conference article › peer-review

Abstract

Cerebral blood flow has potential to be an early biomarker for autism. In this study, we implemented diffuse correlation spectroscopy (DCS) in the BTBR mouse model of autism. Results showed that the autism model had significantly (P < .001) lower cerebral blood flow compared to a control group, approximately 40%. These results show that noninvasive measures of cerebral blood flow through DCS are a potential biomarker for autism.

Original language	English
Article number	JM3A.69
Journal	Optics InfoBase Conference Papers
State	Published - 2022
Event	Clinical and Translational Biophotonics, Translational 2022 - Fort Lauderdale, United States Duration: Apr 24 2022 → Apr 27 2022

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@article{448552d2db334065a0275b6c7de83312,

title = "Quantification of hypoperfusion in autism spectrum disorder assessed by diffuse correlation spectroscopy",

abstract = "Cerebral blood flow has potential to be an early biomarker for autism. In this study, we implemented diffuse correlation spectroscopy (DCS) in the BTBR mouse model of autism. Results showed that the autism model had significantly (P < .001) lower cerebral blood flow compared to a control group, approximately 40\%. These results show that noninvasive measures of cerebral blood flow through DCS are a potential biomarker for autism.",

author = "Benjamin Rinehart and Chien Poon and Ulas Sunar",

note = "Publisher Copyright: {\textcopyright} 2022 The Author(s).; Clinical and Translational Biophotonics, Translational 2022 ; Conference date: 24-04-2022 Through 27-04-2022",

year = "2022",

language = "English",

journal = "Optics InfoBase Conference Papers",

issn = "2162-2701",

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TY - JOUR

T1 - Quantification of hypoperfusion in autism spectrum disorder assessed by diffuse correlation spectroscopy

AU - Rinehart, Benjamin

AU - Poon, Chien

AU - Sunar, Ulas

PY - 2022

Y1 - 2022

N2 - Cerebral blood flow has potential to be an early biomarker for autism. In this study, we implemented diffuse correlation spectroscopy (DCS) in the BTBR mouse model of autism. Results showed that the autism model had significantly (P < .001) lower cerebral blood flow compared to a control group, approximately 40%. These results show that noninvasive measures of cerebral blood flow through DCS are a potential biomarker for autism.

AB - Cerebral blood flow has potential to be an early biomarker for autism. In this study, we implemented diffuse correlation spectroscopy (DCS) in the BTBR mouse model of autism. Results showed that the autism model had significantly (P < .001) lower cerebral blood flow compared to a control group, approximately 40%. These results show that noninvasive measures of cerebral blood flow through DCS are a potential biomarker for autism.

UR - https://www.scopus.com/pages/publications/85136378968

M3 - Conference article

SN - 2162-2701

JO - Optics InfoBase Conference Papers

JF - Optics InfoBase Conference Papers

M1 - JM3A.69

T2 - Clinical and Translational Biophotonics, Translational 2022

Y2 - 24 April 2022 through 27 April 2022

ER -

Quantification of hypoperfusion in autism spectrum disorder assessed by diffuse correlation spectroscopy

Abstract

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