Abstract
Vitexin, a natural flavonuid compound, has extensive pharmacological activity. In recent years, many studies have revealed that vitexin has significant protective effects on central nervous system and peripheral nervous system, including anti-memory impairment, anti-epilepsy, anti-ischemic hypoxic brain damage, anti-depression, analgesia, etc. Vitexin exerts neuroprotective effects through the mechanisms of multiple pathways and multi-targets, such as reducing free radical level, inhibiting neuronal apoptosis, modulating inflammatory factors and related pathways, and regulating neurotransmitters and related receptors. This review mainly discusses the neuroprotective effects of vitexin and its underlying mechanisms.
| Original language | English |
|---|---|
| Pages (from-to) | 1353-1356 |
| Number of pages | 4 |
| Journal | Chinese Pharmacological Bulletin |
| Volume | 32 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 2016 |
Keywords
- Analgesia
- Mechanisms
- Neuroprotection effects
- Receptors
- Review
- Vitexin
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