TY - GEN
T1 - Sensitivity Study on Scattering Media with MRI-Guided Spatial Heterogeneity
AU - Pei, Y.
AU - Graber, H. L.
AU - Lin, F. B.
AU - Barbour, R. L.
N1 - Publisher Copyright: © 1998 Optical Society of America.
PY - 1998
Y1 - 1998
N2 - The sensitivity of NIR optical measurements of the breast, as a function of parameters associated with data collection and of target properties, have been computed from analysis of MRI data. Specific parameters explored include: source condition (DC, 200MHz), view angle (coronal vs. sagittal view), optical contrast of background tissues, contrast of embedded tumor, tumor to breast cross-sectional area ratio, and breast diameter. Results obtained demonstrate the importance of background heterogeneity and previously undocumented an improvement in sensitivity to embedded objects with increasing target diameter. In addition, the sensitivity dependence on the explored parameter space was not found to scale directly with target size.
AB - The sensitivity of NIR optical measurements of the breast, as a function of parameters associated with data collection and of target properties, have been computed from analysis of MRI data. Specific parameters explored include: source condition (DC, 200MHz), view angle (coronal vs. sagittal view), optical contrast of background tissues, contrast of embedded tumor, tumor to breast cross-sectional area ratio, and breast diameter. Results obtained demonstrate the importance of background heterogeneity and previously undocumented an improvement in sensitivity to embedded objects with increasing target diameter. In addition, the sensitivity dependence on the explored parameter space was not found to scale directly with target size.
KW - Light propagation in tissue
KW - Photon migration
KW - Scattering media
UR - https://www.scopus.com/pages/publications/85135931985
M3 - Conference contribution
T3 - Optics InfoBase Conference Papers
SP - 147
EP - 152
BT - Advances in Optical Imaging and Photon Migration, AOIPM 1998
PB - Optica Publishing Group (formerly OSA)
T2 - Advances in Optical Imaging and Photon Migration, AOIPM 1998
Y2 - 8 March 1998
ER -