Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix

S. Shokouhi; P. Vaska; S. Southekal; D. Schlyer; M. Purschke; V. Dzordzhadze; C. Woody; S. Stoll; D. L. Alexoff; D. Rubins; A. Villanueva; S. Krishnamoorthy

Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix

S. Shokouhi
, P. Vaska
, S. Southekal
, D. Schlyer
, M. Purschke
, V. Dzordzhadze
, C. Woody
, S. Stoll
, D. L. Alexoff
, D. Rubins
, A. Villanueva
, S. Krishnamoorthy

Dept of Biomedical Engineering

Stony Brook University

Research output: Contribution to journal › Conference article › peer-review

20 Scopus citations

Abstract

This work describes a fully 3D statistical image reconstruction for the RatCAP (Rat Conscious Animal PET) using a Monte Carlo based system matrix. The RatCAP consists of 12 lutetium oxyorthosilicate (LSO) - avalanche photodiode (APD) detector blocks arranged in a ring of 41.2 mm diameter. Due to the small ring diameter and low number of total lines of response (LORs), the size of a complete system matrix is small in comparison to a typical small animal scanner. This allows incorporation of an accurate, RatCAP-speciflc physical model with the inclusion of crystal penetration, Compton scattering in both rat's brain and detector, attenuation and the realistic event positioning errors. The trade off between the statistical accuracy and the matrix computational time as it relates to the accuracy of image reconstruction will also be discussed.

Original language	English
Article number	M10-136
Pages (from-to)	3901-3905
Number of pages	5
Journal	IEEE Nuclear Science Symposium Conference Record
Volume	6
State	Published - 2004
Event	2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy Duration: Oct 16 2004 → Oct 22 2004

Cite this

Shokouhi, S., Vaska, P., Southekal, S., Schlyer, D., Purschke, M., Dzordzhadze, V., Woody, C., Stoll, S., Alexoff, D. L., Rubins, D., Villanueva, A., & Krishnamoorthy, S. (2004). Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix. IEEE Nuclear Science Symposium Conference Record, 6, 3901-3905. Article M10-136.

@article{1a87a1f2a3704cd8ab8c6857faeccfbd,

title = "Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix",

abstract = "This work describes a fully 3D statistical image reconstruction for the RatCAP (Rat Conscious Animal PET) using a Monte Carlo based system matrix. The RatCAP consists of 12 lutetium oxyorthosilicate (LSO) - avalanche photodiode (APD) detector blocks arranged in a ring of 41.2 mm diameter. Due to the small ring diameter and low number of total lines of response (LORs), the size of a complete system matrix is small in comparison to a typical small animal scanner. This allows incorporation of an accurate, RatCAP-speciflc physical model with the inclusion of crystal penetration, Compton scattering in both rat's brain and detector, attenuation and the realistic event positioning errors. The trade off between the statistical accuracy and the matrix computational time as it relates to the accuracy of image reconstruction will also be discussed.",

author = "S. Shokouhi and P. Vaska and S. Southekal and D. Schlyer and M. Purschke and V. Dzordzhadze and C. Woody and S. Stoll and Alexoff, \{D. L.\} and D. Rubins and A. Villanueva and S. Krishnamoorthy",

year = "2004",

language = "English",

volume = "6",

pages = "3901--3905",

journal = "IEEE Nuclear Science Symposium Conference Record",

issn = "1095-7863",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

note = "2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors ; Conference date: 16-10-2004 Through 22-10-2004",

}

Shokouhi, S, Vaska, P, Southekal, S, Schlyer, D, Purschke, M, Dzordzhadze, V, Woody, C, Stoll, S, Alexoff, DL, Rubins, D, Villanueva, A & Krishnamoorthy, S 2004, 'Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix', IEEE Nuclear Science Symposium Conference Record, vol. 6, M10-136, pp. 3901-3905.

TY - JOUR

T1 - Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix

AU - Shokouhi, S.

AU - Vaska, P.

AU - Southekal, S.

AU - Schlyer, D.

AU - Purschke, M.

AU - Dzordzhadze, V.

AU - Woody, C.

AU - Stoll, S.

AU - Alexoff, D. L.

AU - Rubins, D.

AU - Villanueva, A.

AU - Krishnamoorthy, S.

PY - 2004

Y1 - 2004

N2 - This work describes a fully 3D statistical image reconstruction for the RatCAP (Rat Conscious Animal PET) using a Monte Carlo based system matrix. The RatCAP consists of 12 lutetium oxyorthosilicate (LSO) - avalanche photodiode (APD) detector blocks arranged in a ring of 41.2 mm diameter. Due to the small ring diameter and low number of total lines of response (LORs), the size of a complete system matrix is small in comparison to a typical small animal scanner. This allows incorporation of an accurate, RatCAP-speciflc physical model with the inclusion of crystal penetration, Compton scattering in both rat's brain and detector, attenuation and the realistic event positioning errors. The trade off between the statistical accuracy and the matrix computational time as it relates to the accuracy of image reconstruction will also be discussed.

AB - This work describes a fully 3D statistical image reconstruction for the RatCAP (Rat Conscious Animal PET) using a Monte Carlo based system matrix. The RatCAP consists of 12 lutetium oxyorthosilicate (LSO) - avalanche photodiode (APD) detector blocks arranged in a ring of 41.2 mm diameter. Due to the small ring diameter and low number of total lines of response (LORs), the size of a complete system matrix is small in comparison to a typical small animal scanner. This allows incorporation of an accurate, RatCAP-speciflc physical model with the inclusion of crystal penetration, Compton scattering in both rat's brain and detector, attenuation and the realistic event positioning errors. The trade off between the statistical accuracy and the matrix computational time as it relates to the accuracy of image reconstruction will also be discussed.

UR - https://www.scopus.com/pages/publications/23844558565

M3 - Conference article

SN - 1095-7863

VL - 6

SP - 3901

EP - 3905

JO - IEEE Nuclear Science Symposium Conference Record

JF - IEEE Nuclear Science Symposium Conference Record

M1 - M10-136

T2 - 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors

Y2 - 16 October 2004 through 22 October 2004

ER -

Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix

Abstract

Other files and links

Fingerprint

Cite this