Structure-based tuning of Tm in lipid-like ionic liquids. Insights from Tf2N- salts of gene transfection agents

Arsalan Mirjafari; Samuel M. Murray; Richard A. O’Brien; Alexandra C. Stenson; Kevin N. West; James H. Davis

doi:10.1039/c2cc33609j

Structure-based tuning of T_m in lipid-like ionic liquids. Insights from Tf₂N^- salts of gene transfection agents

Arsalan Mirjafari
, Samuel M. Murray
, Richard A. O’Brien
, Alexandra C. Stenson
, Kevin N. West
, James H. Davis

Chemistry

SUNY Oswego

University of South Alabama

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Ionic liquids of cations bearing two lipid-like aliphatic tails are shown to have values of T_m that can be very low, and that can be tuned up or down by the addition, deletion, or combination of dipolar modules and side-chain double bonds.

Original language	English
Pages (from-to)	7522-7524
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	60
DOIs	https://doi.org/10.1039/c2cc33609j
State	Published - Jul 2 2012

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title = "Structure-based tuning of Tm in lipid-like ionic liquids. Insights from Tf2N- salts of gene transfection agents",

abstract = "Ionic liquids of cations bearing two lipid-like aliphatic tails are shown to have values of Tm that can be very low, and that can be tuned up or down by the addition, deletion, or combination of dipolar modules and side-chain double bonds.",

author = "Arsalan Mirjafari and Murray, \{Samuel M.\} and O{\textquoteright}Brien, \{Richard A.\} and Stenson, \{Alexandra C.\} and West, \{Kevin N.\} and Davis, \{James H.\}",

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AU - Mirjafari, Arsalan

AU - Murray, Samuel M.

AU - O’Brien, Richard A.

AU - Stenson, Alexandra C.

AU - West, Kevin N.

AU - Davis, James H.

PY - 2012/7/2

Y1 - 2012/7/2

N2 - Ionic liquids of cations bearing two lipid-like aliphatic tails are shown to have values of Tm that can be very low, and that can be tuned up or down by the addition, deletion, or combination of dipolar modules and side-chain double bonds.

AB - Ionic liquids of cations bearing two lipid-like aliphatic tails are shown to have values of Tm that can be very low, and that can be tuned up or down by the addition, deletion, or combination of dipolar modules and side-chain double bonds.

UR - https://www.scopus.com/pages/publications/84863700830

U2 - 10.1039/c2cc33609j

DO - 10.1039/c2cc33609j

M3 - Article

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SN - 1359-7345

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SP - 7522

EP - 7524

JO - Chemical Communications

JF - Chemical Communications

IS - 60

ER -

Structure-based tuning of T_m in lipid-like ionic liquids. Insights from Tf₂N^- salts of gene transfection agents

Abstract

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