Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum

Margaret A. Holmes; Frederick S. Buckner; Wesley C. Van Voorhis; Christopher Mehlin; Erica Boni; Thomas N. Earnest; George DeTitta; Joseph Luft; Angela Lauricella; Lori Anderson; Oleksandr Kalyuzhniy; Frank Zucker; Lori W. Schoenfeld; Wim G.J. Hol; Ethan A. Merritt

doi:10.1107/S1744309106005847

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum

Margaret A. Holmes
, Frederick S. Buckner
, Wesley C. Van Voorhis
, Christopher Mehlin
, Erica Boni
, Thomas N. Earnest
, George DeTitta
, Joseph Luft
, Angela Lauricella
, Lori Anderson
, Oleksandr Kalyuzhniy
, Frank Zucker
, Lori W. Schoenfeld
, Wim G.J. Hol
, Ethan A. Merritt

Department of Structural Biology

University at Buffalo

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The structure of a conserved hypothetical protein, PlasmoDB sequence MAL13P1.257 from Plasmodium falciparum, Pfam sequence family PF05907, has been determined as part of the structural genomics effort of the Structural Genomics of Pathogenic Protozoa consortium. The structure was determined by multiple-wavelength anomalous dispersion at 2.17 Å resolution. The structure is almost entirely β-sheet; it consists of 15 β-strands and one short 3₁₀-helix and represents a new protein fold. The packing of the two monomers in the asymmetric unit indicates that the biological unit may be a dimer.

Original language	English
Pages (from-to)	180-185
Number of pages	6
Journal	Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Volume	62
Issue number	3
DOIs	https://doi.org/10.1107/S1744309106005847
State	Published - 2006

Access to Document

10.1107/S1744309106005847

Cite this

Holmes, M. A., Buckner, F. S., Van Voorhis, W. C., Mehlin, C., Boni, E., Earnest, T. N., DeTitta, G., Luft, J., Lauricella, A., Anderson, L., Kalyuzhniy, O., Zucker, F., Schoenfeld, L. W., Hol, W. G. J., & Merritt, E. A. (2006). Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 62(3), 180-185. https://doi.org/10.1107/S1744309106005847

@article{c132eedf5ec94aa4b6cec5dff0d9aaeb,

title = "Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum",

abstract = "The structure of a conserved hypothetical protein, PlasmoDB sequence MAL13P1.257 from Plasmodium falciparum, Pfam sequence family PF05907, has been determined as part of the structural genomics effort of the Structural Genomics of Pathogenic Protozoa consortium. The structure was determined by multiple-wavelength anomalous dispersion at 2.17 {\AA} resolution. The structure is almost entirely β-sheet; it consists of 15 β-strands and one short 310-helix and represents a new protein fold. The packing of the two monomers in the asymmetric unit indicates that the biological unit may be a dimer.",

author = "Holmes, \{Margaret A.\} and Buckner, \{Frederick S.\} and \{Van Voorhis\}, \{Wesley C.\} and Christopher Mehlin and Erica Boni and Earnest, \{Thomas N.\} and George DeTitta and Joseph Luft and Angela Lauricella and Lori Anderson and Oleksandr Kalyuzhniy and Frank Zucker and Schoenfeld, \{Lori W.\} and Hol, \{Wim G.J.\} and Merritt, \{Ethan A.\}",

year = "2006",

doi = "10.1107/S1744309106005847",

language = "English",

volume = "62",

pages = "180--185",

journal = "Acta Crystallographica Section F: Structural Biology and Crystallization Communications",

issn = "1744-3091",

publisher = "John Wiley and Sons Ltd",

number = "3",

}

Holmes, MA, Buckner, FS, Van Voorhis, WC, Mehlin, C, Boni, E, Earnest, TN, DeTitta, G, Luft, J, Lauricella, A, Anderson, L, Kalyuzhniy, O, Zucker, F, Schoenfeld, LW, Hol, WGJ & Merritt, EA 2006, 'Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, vol. 62, no. 3, pp. 180-185. https://doi.org/10.1107/S1744309106005847

TY - JOUR

T1 - Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum

AU - Holmes, Margaret A.

AU - Buckner, Frederick S.

AU - Van Voorhis, Wesley C.

AU - Mehlin, Christopher

AU - Boni, Erica

AU - Earnest, Thomas N.

AU - DeTitta, George

AU - Luft, Joseph

AU - Lauricella, Angela

AU - Anderson, Lori

AU - Kalyuzhniy, Oleksandr

AU - Zucker, Frank

AU - Schoenfeld, Lori W.

AU - Hol, Wim G.J.

AU - Merritt, Ethan A.

PY - 2006

Y1 - 2006

N2 - The structure of a conserved hypothetical protein, PlasmoDB sequence MAL13P1.257 from Plasmodium falciparum, Pfam sequence family PF05907, has been determined as part of the structural genomics effort of the Structural Genomics of Pathogenic Protozoa consortium. The structure was determined by multiple-wavelength anomalous dispersion at 2.17 Å resolution. The structure is almost entirely β-sheet; it consists of 15 β-strands and one short 310-helix and represents a new protein fold. The packing of the two monomers in the asymmetric unit indicates that the biological unit may be a dimer.

AB - The structure of a conserved hypothetical protein, PlasmoDB sequence MAL13P1.257 from Plasmodium falciparum, Pfam sequence family PF05907, has been determined as part of the structural genomics effort of the Structural Genomics of Pathogenic Protozoa consortium. The structure was determined by multiple-wavelength anomalous dispersion at 2.17 Å resolution. The structure is almost entirely β-sheet; it consists of 15 β-strands and one short 310-helix and represents a new protein fold. The packing of the two monomers in the asymmetric unit indicates that the biological unit may be a dimer.

UR - https://www.scopus.com/pages/publications/33645745151

U2 - 10.1107/S1744309106005847

DO - 10.1107/S1744309106005847

M3 - Article

C2 - 16511296

SN - 1744-3091

VL - 62

SP - 180

EP - 185

JO - Acta Crystallographica Section F: Structural Biology and Crystallization Communications

JF - Acta Crystallographica Section F: Structural Biology and Crystallization Communications

IS - 3

ER -

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum

Abstract

Access to Document

Other files and links

Fingerprint

Cite this