1H, 13C, and 15N NMR assignments of a Drosophila Hedgehog autoprocessing domain

Jian Xie; Zhenming Du; Brian Callahan; Marlene Belfort; Chunyu Wang

doi:10.1007/s12104-013-9500-8

¹H, ¹³C, and ¹⁵N NMR assignments of a Drosophila Hedgehog autoprocessing domain

Jian Xie
, Zhenming Du
, Brian Callahan
, Marlene Belfort
, Chunyu Wang

Binghamton University, University at Albany

Rensselaer Polytechnic Institute

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [¹³C, ¹⁵N]-labeled and [²H, ¹³C, ¹⁵N])-labeled proteins.

Original language	English
Pages (from-to)	279-281
Number of pages	3
Journal	Biomolecular NMR Assignments
Volume	8
Issue number	2
DOIs	https://doi.org/10.1007/s12104-013-9500-8
State	Published - Oct 1 2014

Keywords

Assignments
Autoprocessing
Drosophila
Hedgehog
NMR

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10.1007/s12104-013-9500-8

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title = "1H, 13C, and 15N NMR assignments of a Drosophila Hedgehog autoprocessing domain",

abstract = "The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [13C, 15N]-labeled and [2H, 13C, 15N])-labeled proteins.",

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author = "Jian Xie and Zhenming Du and Brian Callahan and Marlene Belfort and Chunyu Wang",

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T1 - 1H, 13C, and 15N NMR assignments of a Drosophila Hedgehog autoprocessing domain

AU - Xie, Jian

AU - Du, Zhenming

AU - Callahan, Brian

AU - Belfort, Marlene

AU - Wang, Chunyu

PY - 2014/10/1

Y1 - 2014/10/1

N2 - The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [13C, 15N]-labeled and [2H, 13C, 15N])-labeled proteins.

AB - The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [13C, 15N]-labeled and [2H, 13C, 15N])-labeled proteins.

KW - Assignments

KW - Autoprocessing

KW - Drosophila

KW - Hedgehog

KW - NMR

UR - https://www.scopus.com/pages/publications/84878770816

U2 - 10.1007/s12104-013-9500-8

DO - 10.1007/s12104-013-9500-8

M3 - Article

C2 - 23765287

SN - 1874-2718

VL - 8

SP - 279

EP - 281

JO - Biomolecular NMR Assignments

JF - Biomolecular NMR Assignments

IS - 2

ER -

¹H, ¹³C, and ¹⁵N NMR assignments of a Drosophila Hedgehog autoprocessing domain

Abstract

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