Synthesis of 2-C-Methyl-D-Erythritol 2,4-Cyclopyrophosphate

José Luis Giner; William V. Ferris

doi:10.1021/ol025661a

Synthesis of 2-C-Methyl-D-Erythritol 2,4-Cyclopyrophosphate

José Luis Giner
, William V. Ferris

Chemistry

College of Environmental Science & Forestry

SUNY College of Environmental Science and Forestry

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

matrix presented The synthesis of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate, a biochemical intermediate in the deoxyxylulose pathway of isoprenoid biosynthesis, was accomplished in four steps. Bisphosphorylation of 2-C-methyl-D-erythritol 1,3-diacetate, followed by carbodiimide cyclization and deprotection, led to the title compound in 42% overall yield.

Original language	English
Pages (from-to)	1225-1226
Number of pages	2
Journal	Organic Letters
Volume	4
Issue number	7
DOIs	https://doi.org/10.1021/ol025661a
State	Published - Apr 4 2002

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title = "Synthesis of 2-C-Methyl-D-Erythritol 2,4-Cyclopyrophosphate",

abstract = "matrix presented The synthesis of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate, a biochemical intermediate in the deoxyxylulose pathway of isoprenoid biosynthesis, was accomplished in four steps. Bisphosphorylation of 2-C-methyl-D-erythritol 1,3-diacetate, followed by carbodiimide cyclization and deprotection, led to the title compound in 42\% overall yield.",

author = "Giner, \{Jos{\'e} Luis\} and Ferris, \{William V.\}",

year = "2002",

month = apr,

day = "4",

doi = "10.1021/ol025661a",

language = "English",

volume = "4",

pages = "1225--1226",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Synthesis of 2-C-Methyl-D-Erythritol 2,4-Cyclopyrophosphate

AU - Giner, José Luis

AU - Ferris, William V.

PY - 2002/4/4

Y1 - 2002/4/4

N2 - matrix presented The synthesis of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate, a biochemical intermediate in the deoxyxylulose pathway of isoprenoid biosynthesis, was accomplished in four steps. Bisphosphorylation of 2-C-methyl-D-erythritol 1,3-diacetate, followed by carbodiimide cyclization and deprotection, led to the title compound in 42% overall yield.

AB - matrix presented The synthesis of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate, a biochemical intermediate in the deoxyxylulose pathway of isoprenoid biosynthesis, was accomplished in four steps. Bisphosphorylation of 2-C-methyl-D-erythritol 1,3-diacetate, followed by carbodiimide cyclization and deprotection, led to the title compound in 42% overall yield.

UR - https://www.scopus.com/pages/publications/0037018469

U2 - 10.1021/ol025661a

DO - 10.1021/ol025661a

M3 - Article

C2 - 11922824

SN - 1523-7060

VL - 4

SP - 1225

EP - 1226

JO - Organic Letters

JF - Organic Letters

IS - 7

ER -

Synthesis of 2-C-Methyl-D-Erythritol 2,4-Cyclopyrophosphate

Abstract

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