The effects of drugs on Pluronic F127 structure

P. K. Sharma; S. R. Bhatia

The effects of drugs on Pluronic F127 structure

P. K. Sharma
, S. R. Bhatia

Chemistry

Stony Brook University

University of Massachusetts

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

Small-angle neutron scattering was used to study the effects of several drugs and additives on the aggregation number, core and corona radii and interparticle interaction distance of Pluronic F127 micelles. Depending upon their molecular weight and partition coefficient, these drugs were found to cause changes in the micellar structure. Our findings have implications on the performance and design of F127 drug delivery formulations.

Original language	English
Pages (from-to)	228-229
Number of pages	2
Journal	Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
Volume	30
State	Published - 2004
Event	Proceedings of the IEEE 30th Annual Northeast Bioengineering Conference - Springfield, MA, United States Duration: Apr 17 2004 → Apr 18 2004

Cite this

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title = "The effects of drugs on Pluronic F127 structure",

abstract = "Small-angle neutron scattering was used to study the effects of several drugs and additives on the aggregation number, core and corona radii and interparticle interaction distance of Pluronic F127 micelles. Depending upon their molecular weight and partition coefficient, these drugs were found to cause changes in the micellar structure. Our findings have implications on the performance and design of F127 drug delivery formulations.",

author = "Sharma, \{P. K.\} and Bhatia, \{S. R.\}",

year = "2004",

language = "English",

volume = "30",

pages = "228--229",

journal = "Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC",

issn = "1071-121X",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

note = "Proceedings of the IEEE 30th Annual Northeast Bioengineering Conference ; Conference date: 17-04-2004 Through 18-04-2004",

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TY - JOUR

T1 - The effects of drugs on Pluronic F127 structure

AU - Sharma, P. K.

AU - Bhatia, S. R.

PY - 2004

Y1 - 2004

N2 - Small-angle neutron scattering was used to study the effects of several drugs and additives on the aggregation number, core and corona radii and interparticle interaction distance of Pluronic F127 micelles. Depending upon their molecular weight and partition coefficient, these drugs were found to cause changes in the micellar structure. Our findings have implications on the performance and design of F127 drug delivery formulations.

AB - Small-angle neutron scattering was used to study the effects of several drugs and additives on the aggregation number, core and corona radii and interparticle interaction distance of Pluronic F127 micelles. Depending upon their molecular weight and partition coefficient, these drugs were found to cause changes in the micellar structure. Our findings have implications on the performance and design of F127 drug delivery formulations.

UR - https://www.scopus.com/pages/publications/2942616787

M3 - Conference article

SN - 1071-121X

VL - 30

SP - 228

EP - 229

JO - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC

JF - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC

T2 - Proceedings of the IEEE 30th Annual Northeast Bioengineering Conference

Y2 - 17 April 2004 through 18 April 2004

ER -

The effects of drugs on Pluronic F127 structure

Abstract

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