The paradox of overnutrition in aging and cognition

Roger A. Fielding; John Gunstad; Deborah R. Gustafson; Steven B. Heymsfield; John G. Kral; Lenore J. Launer; Josef Penninger; David I.W. Phillips; Nikolaos Scarmeas

doi:10.1111/nyas.12138

The paradox of overnutrition in aging and cognition

Roger A. Fielding
, John Gunstad
, Deborah R. Gustafson
, Steven B. Heymsfield
, John G. Kral
, Lenore J. Launer
, Josef Penninger
, David I.W. Phillips
, Nikolaos Scarmeas

Neurology

SUNY Downstate Health Sciences University

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Populations of many countries are becoming increasingly overweight and obese, driven largely by excessive calorie intake and reduced physical activity; greater body mass is accompanied by epidemic levels of comorbid metabolic diseases. At the same time, individuals are living longer. The combination of aging and the increased prevalence of metabolic disease is associated with increases in aging-related comorbid diseases such as Alzheimer's disease, cerebrovascular dementia, and sarcopenia. Here, correlative and causal links between diseases of overnutrition and diseases of aging and cognition are explored.

Original language	English
Pages (from-to)	31-43
Number of pages	13
Journal	Annals of the New York Academy of Sciences
Volume	1287
Issue number	1
DOIs	https://doi.org/10.1111/nyas.12138
State	Published - May 2013

Keywords

Alzheimer's disease
Cognitive decline
Obesity
Overnutrition
Sarcopenia

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10.1111/nyas.12138

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AU - Fielding, Roger A.

AU - Gunstad, John

AU - Gustafson, Deborah R.

AU - Heymsfield, Steven B.

AU - Kral, John G.

AU - Launer, Lenore J.

AU - Penninger, Josef

AU - Phillips, David I.W.

AU - Scarmeas, Nikolaos

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AB - Populations of many countries are becoming increasingly overweight and obese, driven largely by excessive calorie intake and reduced physical activity; greater body mass is accompanied by epidemic levels of comorbid metabolic diseases. At the same time, individuals are living longer. The combination of aging and the increased prevalence of metabolic disease is associated with increases in aging-related comorbid diseases such as Alzheimer's disease, cerebrovascular dementia, and sarcopenia. Here, correlative and causal links between diseases of overnutrition and diseases of aging and cognition are explored.

KW - Alzheimer's disease

KW - Cognitive decline

KW - Obesity

KW - Overnutrition

KW - Sarcopenia

UR - https://www.scopus.com/pages/publications/84878425102

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IS - 1

ER -

The paradox of overnutrition in aging and cognition

Abstract

Keywords

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