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Three-Dimensional Extracellular Matrix Protein Hydrogels for Human Trabecular Meshwork Cell Studies

  • SUNY Upstate Medical University
  • Georgia Institute of Technology
  • Syracuse University

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations

Abstract

The extracellular microenvironment plays a crucial role in regulating a wide range of cell behaviors. Biopolymer hydrogels are ideally suited to present a realistic three-dimensional extracellular milieu to cells in vitro. Here, we describe the fabrication and use of soft tissue-mimetic extracellular matrix protein hydrogels for investigations of human trabecular meshwork cell biology.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages17-29
Number of pages13
DOIs
StatePublished - 2025

Publication series

NameMethods in Molecular Biology
Volume2858

Keywords

  • Bioengineering
  • Biopolymers
  • Glaucoma
  • Outflow tract
  • Photo-crosslinking

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