Ultrashort echo time MRI of cortical bone at 7 Tesla field strength: A feasibility study

Roland Krug; Peder Eric Zufall Larson; Chunsheng Wang; Andrew J. Burghardt; Douglas A.C. Kelley; Thomas M. Link; Xiaoliang Zhang; Daniel B. Vigneron; Sharmila Majumdar

doi:10.1002/jmri.22648

Ultrashort echo time MRI of cortical bone at 7 Tesla field strength: A feasibility study

Roland Krug
, Peder Eric Zufall Larson
, Chunsheng Wang
, Andrew J. Burghardt
, Douglas A.C. Kelley
, Thomas M. Link
, Xiaoliang Zhang
, Daniel B. Vigneron
, Sharmila Majumdar

Department of Biomedical Engineering

University at Buffalo

University of California at San Francisco
GE Healthcare United States

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Purpose: To implement and examine the feasibility of a three-dimensional (3D) ultrashort TE (UTE) sequence on a 7 Tesla (T) clinical MR scanner in comparison with 3T MRI at high isotropic resolution. Materials and Methods: Using an in-house built saddle coil at both field strengths we have imaged mid-diaphysial sections of five fresh cadaveric specimens of the distal tibia. An additional in vivo scan was performed at 7 Tesla using a quadrature knee coil. Results: Using the same type of saddle coil at both field strengths, a significant increase in SNR at 7T compared with 3T (factor 1.7) was found. Significantly shorter T2* values were found at the higher field strength (T2* = 552.2 ± 126 μs at 7T versus T2* = 1163 ± 391 μs at 3T). Conclusion: UHF MRI at 7T has great potential for imaging tissues with short T2.

Original language	English
Pages (from-to)	691-695
Number of pages	5
Journal	Journal of Magnetic Resonance Imaging
Volume	34
Issue number	3
DOIs	https://doi.org/10.1002/jmri.22648
State	Published - Sep 2011

Keywords

7 Tesla
cortical bone
ultra-short MRI

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10.1002/jmri.22648

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title = "Ultrashort echo time MRI of cortical bone at 7 Tesla field strength: A feasibility study",

abstract = "Purpose: To implement and examine the feasibility of a three-dimensional (3D) ultrashort TE (UTE) sequence on a 7 Tesla (T) clinical MR scanner in comparison with 3T MRI at high isotropic resolution. Materials and Methods: Using an in-house built saddle coil at both field strengths we have imaged mid-diaphysial sections of five fresh cadaveric specimens of the distal tibia. An additional in vivo scan was performed at 7 Tesla using a quadrature knee coil. Results: Using the same type of saddle coil at both field strengths, a significant increase in SNR at 7T compared with 3T (factor 1.7) was found. Significantly shorter T2* values were found at the higher field strength (T2* = 552.2 ± 126 μs at 7T versus T2* = 1163 ± 391 μs at 3T). Conclusion: UHF MRI at 7T has great potential for imaging tissues with short T2.",

keywords = "7 Tesla, cortical bone, ultra-short MRI",

author = "Roland Krug and Larson, \{Peder Eric Zufall\} and Chunsheng Wang and Burghardt, \{Andrew J.\} and Kelley, \{Douglas A.C.\} and Link, \{Thomas M.\} and Xiaoliang Zhang and Vigneron, \{Daniel B.\} and Sharmila Majumdar",

year = "2011",

month = sep,

doi = "10.1002/jmri.22648",

language = "English",

volume = "34",

pages = "691--695",

journal = "Journal of Magnetic Resonance Imaging",

issn = "1053-1807",

publisher = "John Wiley and Sons Inc.",

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TY - JOUR

T1 - Ultrashort echo time MRI of cortical bone at 7 Tesla field strength

T2 - A feasibility study

AU - Krug, Roland

AU - Larson, Peder Eric Zufall

AU - Wang, Chunsheng

AU - Burghardt, Andrew J.

AU - Kelley, Douglas A.C.

AU - Link, Thomas M.

AU - Zhang, Xiaoliang

AU - Vigneron, Daniel B.

AU - Majumdar, Sharmila

PY - 2011/9

Y1 - 2011/9

N2 - Purpose: To implement and examine the feasibility of a three-dimensional (3D) ultrashort TE (UTE) sequence on a 7 Tesla (T) clinical MR scanner in comparison with 3T MRI at high isotropic resolution. Materials and Methods: Using an in-house built saddle coil at both field strengths we have imaged mid-diaphysial sections of five fresh cadaveric specimens of the distal tibia. An additional in vivo scan was performed at 7 Tesla using a quadrature knee coil. Results: Using the same type of saddle coil at both field strengths, a significant increase in SNR at 7T compared with 3T (factor 1.7) was found. Significantly shorter T2* values were found at the higher field strength (T2* = 552.2 ± 126 μs at 7T versus T2* = 1163 ± 391 μs at 3T). Conclusion: UHF MRI at 7T has great potential for imaging tissues with short T2.

AB - Purpose: To implement and examine the feasibility of a three-dimensional (3D) ultrashort TE (UTE) sequence on a 7 Tesla (T) clinical MR scanner in comparison with 3T MRI at high isotropic resolution. Materials and Methods: Using an in-house built saddle coil at both field strengths we have imaged mid-diaphysial sections of five fresh cadaveric specimens of the distal tibia. An additional in vivo scan was performed at 7 Tesla using a quadrature knee coil. Results: Using the same type of saddle coil at both field strengths, a significant increase in SNR at 7T compared with 3T (factor 1.7) was found. Significantly shorter T2* values were found at the higher field strength (T2* = 552.2 ± 126 μs at 7T versus T2* = 1163 ± 391 μs at 3T). Conclusion: UHF MRI at 7T has great potential for imaging tissues with short T2.

KW - 7 Tesla

KW - cortical bone

KW - ultra-short MRI

UR - https://www.scopus.com/pages/publications/80051929337

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DO - 10.1002/jmri.22648

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JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

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ER -

Ultrashort echo time MRI of cortical bone at 7 Tesla field strength: A feasibility study

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